Adriana Tremoulet, M.D., M.A.S.

Bio

Dr. Adriana Tremoulet is the associate director of the Kawasaki Disease Research Center at UC San Diego. In this role, she cares for nearly 1,500 children with Kawasaki disease in San Diego County and an additional 90 children a year hospitalized at Rady Children's Hospital-San Diego .

Dr. Tremoulet graduated from Harvard University with a major in biochemistry and attended medical school at the University of California, Los Angeles. During medical school, she spent a year as a fellow in the National Institutes of Health Clinical Research Training Program. She then completed her residency at Cedars-Sinai Medical Center and her pediatric infectious disease fellowship at UC San Diego.

In 2013, Dr. Tremoulet was appointed as the associate director of clinical research at Rady Children's. She is also the site principal investigator for the National Institute of Child Health and Human Development-funded Pediatric Trials Network and Research Program in Developmental Pharmacology at UC San Diego. Dr. Tremoulet has led Phase I through III clinical trials, including a Food and Drug Administration Orphan Products grant-funded Phase III clinical trial on the use of infliximab as adjunctive primary therapy in Kawasaki disease.

Publications

Heterozygous BTNL8 variants in individuals with multisystem inflammatory syndrome in children (MIS-C).
Bellos E, Santillo D, Vantourout P, Jackson HR, Duret A, Hearn H, Seeleuthner Y, Talouarn E, Hodeib S, Patel H, Powell O, Yeoh S, Mustafa S, Habgood-Coote D, Nichols S, Estramiana Elorrieta L, D'Souza G, Wright VJ, Estrada-Rivadeneyra D, Tremoulet AH, Dummer KB, Netea SA, Condino-Neto A, Lau YL, Núñez Cuadros E, Toubiana J, Holanda Pena M, Rieux-Laucat F, Luyt CE, Haerynck F, Mège JL, Chakravorty S, Haddad E, Morin MP, Metin Akcan Ö, Keles S, Emiroglu M, Alkan G, Tüter Öz SK, Elmas Bozdemir S, Morelle G, Volokha A, Kendir-Demirkol Y, Sözeri B, Coskuner T, Yahsi A, Gulhan B, Kanik-Yuksek S, Bayhan GI, Ozkaya-Parlakay A, Yesilbas O, Hatipoglu N, Ozcelik T, Belot A, Chopin E, Barlogis V, Sevketoglu E, Menentoglu E, Gayretli Aydin ZG, Bloomfield M, AlKhater SA, Cyrus C, Stepanovskiy Y, Bondarenko A, Öz FN, Polat M, Fremuth J, Lebl J, Geraldo A, Jouanguy E, COVID-19 Human Genetic Effort, DIAMONDS, EUCLIDS, Carter MJ, Wellman P, Peters M, Pérez de Diego R, Edwards LA, Chiu C, Noursadeghi M, Bolze A, Shimizu C, Kaforou M, Hamilton MS, Herberg JA, Schmitt EG, Rodriguez-Palmero A, Pujol A, Kim J, Cobat A, Abel L, Zhang SY, Casanova JL, Kuijpers TW, Burns JC, Levin M, Hayday AC, Sancho-Shimizu V

A Thrombolytic Protocol of Bivalirudin for Giant Coronary Artery Aneurysms and Thrombosis in Kawasaki Disease.
Wang H, Dummer K, Tremoulet AH, Newburger J, Burns JC, VanderPluym C

The long-term vascular and myocardial outcomes in selected Kawasaki disease patients with regression of giant coronary artery aneurysms.
Kung SC, Miyata K, Colvert GM, Kahn AM, Daniels LB, Hoshino S, Dummer KB, Golding IF, Roberts S, Shimizu C, Tremoulet AH, McVeigh ER, Gordon JB, Burns JC

Macrophage Activation Syndrome in MIS-C.
Gámez-González LB, Murata C, García-Silva J, Ulloa-Gutierrez R, Márquez-Aguirre M, Ríos-Olivares I, Faugier-Fuentes E, Domínguez-Rojas JA, Yock-Corrales A, Álvarez-Olmos MI, Fernández-Sarmiento J, Velasquez-Méndez M, Ivankovich-Escoto G, Tremoulet AH, Yamazaki-Nakashimada MA, REKAMLATINA-3 MIS-C STUDY GROUP INVESTIGATORS

Update on Diagnosis and Management of Kawasaki Disease: A Scientific Statement From the American Heart Association.
Jone PN, Tremoulet A, Choueiter N, Dominguez SR, Harahsheh AS, Mitani Y, Zimmerman M, Lin MT, Friedman KG, American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee of the Council on Lifelong Congenital Heart Disease and Heart Health in the Young; Council on Cardiovascular and Stroke Nursing; Council on Cardiovascular Radiology and Intervention; and Council on Clinical Cardiology

Plasma cell-free RNA signatures of inflammatory syndromes in children.
Loy CJ, Servellita V, Sotomayor-Gonzalez A, Bliss A, Lenz JS, Belcher E, Suslovic W, Nguyen J, Williams ME, Oseguera M, Gardiner MA, P.E.M.K.D.R.G., C.H.A.R.M.S. the Study Group, Choi JH, Hsiao HM, Wang H, Kim J, Shimizu C, Tremoulet AH, Delaney M, DeBiasi RL, Rostad CA, Burns JC, Chiu CY, De Vlaminck I

Multisystem inflammatory syndrome in children across 16 Latin American countries: A multicenter study from the REKAMLATINA Network.
García-Silva J, Ulloa-Gutierrez R, Ivankovich-Escoto G, Yamazaki-Nakashimada MA, Faugier-Fuentes E, Del Águila O, Camacho-Moreno G, Estripeaut D, Gutiérrez IF, Castillo-Bustamante D, Luciani K, Fabi M, Espada G, Álvarez-Olmos MI, Silfa C, Pérez-Camacho P, Duarte-Passos S, Cervi MC, Martínez-Ramírez RO, Cantillano EM, Llamas-Guillén BA, Velásquez-Méndez M, Saltigeral-Simental P, Criales J, Fernández-Sarmiento J, Chacon-Cruz E, García-Domínguez M, Aguilar KLB, Villarreal-Treviño AV, Tremoulet AH, REKAMLATINA-3 MIS-C Study Group Investigators

Risk Factors Associated with Intensive Care Admission in Children with Severe Acute Respiratory Syndrome Coronavirus 2-Related Multisystem Inflammatory Syndrome (MIS-C) in Latin America: A Multicenter Observational Study of the REKAMLATINA Network.
Fernández-Sarmiento J, Acevedo L, Niño-Serna LF, Boza R, García-Silva J, Yock-Corrales A, Yamazaki-Nakashimada MA, Faugier-Fuentes E, Del Águila O, Camacho-Moreno G, Estripeaut D, Gutiérrez IF, Luciani K, Espada G, Álvarez-Olmos MI, Pérez-Camacho P, Duarte-Passos S, Cervi MC, Cantillano EM, Llamas-Guillén BA, Saltigeral-Simental P, Criales J, Chacon-Cruz E, García-Domínguez M, Aguilar KLB, Jarovsky D, Ivankovich-Escoto G, Tremoulet AH, Ulloa-Gutierrez R, REKAMLATINA-3 Study Group Investigators 32

Swissped-RECOVERY: masked independent adjudication for the interpretation of non-randomised treatment in a two-arm open-label randomised controlled trial (methylprednisolone vs immunoglobulins) in Paediatric Inflammatory Multisystem Syndrome Temporally Associated with SARS-CoV-2 (PIMS-TS) involving 10 secondary and tertiary paediatric hospitals in Switzerland.
Schöbi N, Sanchez C, Welzel T, Bamford A, Webb K, Rojo P, Tremoulet A, Atkinson A, Schlapbach LJ, Bielicki JA, Swissped-RECOVERY trial group

Plasma Cell-free RNA Signatures of Inflammatory Syndromes in Children.
Loy CJ, Servellita V, Sotomayor-Gonzalez A, Bliss A, Lenz J, Belcher E, Suslovic W, Nguyen J, Williams ME, Oseguera M, Gardiner MA, Pediatric Emergency Medicine Kawasaki Disease Research Group (PEMKDRG), CHARMS Study Group, Choi JH, Hsiao HM, Wang H, Kim J, Shimizu C, Tremoulet A, Delaney M, DeBiasi RL, Rostad CA, Burns JC, Chiu CY, Vlaminck I

More on Pre-Covid-19, SARS-CoV-2-Negative MIS-C.
Franco A, Tremoulet A, Burns JC

SARS-CoV-2 variants are associated with different clinical courses in children with MIS-C.
Moreno Rojas AF, Bainto E, Harvey H, Tremoulet AH, Burns JC, Dummer KB

Intravenous immunoglobulin resistance in Kawasaki disease patients: prediction using clinical data.
Lam JY, Song MS, Kim GB, Shimizu C, Bainto E, Tremoulet AH, Nemati S, Burns JC

Addressing sequential and concurrent treatment regimens in a small n sequential, multiple assignment, randomized trial (snSMART) in the MISTIC study.
Cheng Y, Tremoulet A, Burns J, Jain S

Clinical Presentation and Outcomes of Kawasaki Disease in Children from Latin America: A Multicenter Observational Study from the REKAMLATINA Network.
Narayan HK, Lizcano A, Lam-Hine T, Ulloa-Gutierrez R, Bainto EV, Garrido-García LM, Estripeaut D, Del Aguila O, Gómez V, Faugier-Fuentes E, Miño-León G, Beltrán S, Cofré F, Chacon-Cruz E, Saltigeral-Simental P, Martínez-Medina L, Dueñas L, Luciani K, Rodríguez-Quiroz FJ, Camacho Moreno G, Viviani T, Alvarez-Olmos MI, Marques HHS, López-Medina E, Pirez MC, Tremoulet AH, Kawasaki Disease REKAMLATINA Network Study Group

Coronary Sinus Thrombosis and Post-Myocardial Infarction Syndrome in Kawasaki Disease: Rare Causes of Pericardial Effusion.
Wang H, Pancheri JM, Appleton RS, Tremoulet AH, Burns JC, Dummer KB

DOACs in Patients With Giant Coronary Artery Aneurysms After Kawasaki Disease.
Dummer KB, Miyata K, Shimizu C, Tremoulet AH, Gleason J, Gordon JB, Burns JC

Subgroups of children with Kawasaki disease: a data-driven cluster analysis.
Wang H, Shimizu C, Bainto E, Hamilton S, Jackson HR, Estrada-Rivadeneyra D, Kaforou M, Levin M, Pancheri JM, Dummer KB, Tremoulet AH, Burns JC

Infliximab for intensification of primary therapy for patients with Kawasaki disease and coronary artery aneurysms at diagnosis.
Miyata K, Bainto EV, Sun X, Jain S, Dummer KB, Burns JC, Tremoulet AH

Diagnosis of childhood febrile illness using a multi-class blood RNA molecular signature.
Habgood-Coote D, Wilson C, Shimizu C, Barendregt AM, Philipsen R, Galassini R, Calle IR, Workman L, Agyeman PKA, Ferwerda G, Anderson ST, van den Berg JM, Emonts M, Carrol ED, Fink CG, de Groot R, Hibberd ML, Kanegaye J, Nicol MP, Paulus S, Pollard AJ, Salas A, Secka F, Schlapbach LJ, Tremoulet AH, Walther M, Zenz W, Pediatric Emergency Medicine Kawasaki Disease Research Group (PEMKDRG), UK Kawasaki Genetics consortium, GENDRES consortium, EUCLIDS consortium, PERFORM consortium, Van der Flier M, Zar HJ, Kuijpers T, Burns JC, Martinón-Torres F, Wright VJ, Coin LJM, Cunnington AJ, Herberg JA, Levin M, Kaforou M

Endothelial Cell Response in Kawasaki Disease and Multisystem Inflammatory Syndrome in Children.
Kim J, Shimizu C, He M, Wang H, Hoffman HM, Tremoulet AH, Shyy JY, Burns JC

A Deep Learning Framework for Image-Based Screening of Kawasaki Disease.
Lam JY, Kanegaye JT, Xu E, Gardiner MA, Burns JC, Nemati S, Tremoulet AH

Diagnosis of Multisystem Inflammatory Syndrome in Children by a Whole-Blood Transcriptional Signature.
Jackson HR, Miglietta L, Habgood-Coote D, D'Souza G, Shah P, Nichols S, Vito O, Powell O, Davidson MS, Shimizu C, Agyeman PKA, Beudeker CR, Brengel-Pesce K, Carrol ED, Carter MJ, De T, Eleftheriou I, Emonts M, Epalza C, Georgiou P, De Groot R, Fidler K, Fink C, van Keulen D, Kuijpers T, Moll H, Papatheodorou I, Paulus S, Pokorn M, Pollard AJ, Rivero-Calle I, Rojo P, Secka F, Schlapbach LJ, Tremoulet AH, Tsolia M, Usuf E, Van Der Flier M, Von Both U, Vermont C, Yeung S, Zavadska D, Zenz W, Coin LJM, Cunnington A, Burns JC, Wright V, Martinon-Torres F, Herberg JA, Rodriguez-Manzano J, Kaforou M, Levin M

Evaluation of Autoantibody Binding to Cardiac Tissue in Multisystem Inflammatory Syndrome in Children and COVID-19 Vaccination-Induced Myocarditis.
Patel H, Sintou A, Chowdhury RA, Rothery S, Iacob AO, Prasad S, Rainer PP, Martinón-Torres F, Sancho-Shimizu V, Shimizu C, Dummer K, Tremoulet AH, Burns JC, Sattler S, Levin M, DIAMONDS consortium

Transfer of antibiotics and their metabolites in human milk: Implications for infant health and microbiota.
Thomas SP, Denizer E, Zuffa S, Best BM, Bode L, Chambers CD, Dorrestein PC, Liu GY, Momper JD, Nizet V, Tsunoda SM, Tremoulet AH

See the full listing of this physician's publications on PubMed, a service of the National Library of Medicine.

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