Methodology
Clotting Assay; Clot Detection; Chromogenic Substrate; RVVT-based Assay (Clot-based)
Synonyms
Protein C Activity; Protein S Activity; Antithrombin III Activity (AT3); Activated Protein C-Resistance
Specimen Type
Plasma
Performing Lab
Quest Diagnostics San Juan Capistrano
Epic ID
LAB01616
Collection Information
Specimen Required
(three-six) 1.8 mL or (two-four) 2.7 mL Blood
Container Type
Light Blue (Sodium Citrate)
Processing Information - Lab Use Only
Transport Temperature
Frozen-Only
Specimen Stability
Room Temp: Unacceptable; Refrigerated: Unacceptable; Frozen: 6 Months
Test Volume Required
5 mL Platelet-Poor Plasma
Minimum Test Volume
2.5 mL Platelet-Poor Plasma
Processing Instructions
Platelet poor plasma: Centrifuge light blue-top tube 15 minutes at approximately 1500 g within 60 minutes of collection. Using a plastic pipette, remove plasma, taking care to avoid the WBC/platelet buffy layer and place into a plastic vial. Centrifuge a second time and transfer platelet-poor plasma into a new plastic vial. Plasma must be free of platelets (<10,000/mcl). Freeze immediately and send frozen.
Included Tests
Protein C Activity, Protein S Activity, Antithrombin III Activity (AT3) and Activated Protein C Resistance.
CPT Codes
85300, 85303, 85306, 85307
Revised
08-18-19
Initials
SL